Biostimulator

DEFINISSE®BIOSTIMULATOR

PrecisionCollagenRemodelingWithPDLLA

What Is Definisse® Injectable Biostimulator?

Definisse® is an advanced PDLLA (poly-D,L-lactic acid) biostimulator designed to rebuild collagen, firm lax skin, restore natural lift and improve deep structural support — with exceptional smoothness and long-lasting results. Created by the makers of Definisse Threads, this injectable biostimulator is engineered for Natural structural rejuvenation, Improved skin elasticity, Long-term collagen remodelling, Soft, elegant lifting, Midface + jawline support, and Menopause-related collagen decline. It is one of the most precise, refined biostimulators available today.

Why Definisse Fits Perfectly With the ULANDA Philosophy

Definisse is a true regenerative treatment — not a filler and not a quick fix.

Regeneration over correction
Architecture over artificial volume
Fibroblast activation for long-term change
Natural, elegant enhancement
Support for perimenopause + menopause ageing
Scientific integrity and biologically aligned design

Definisse is particularly valued for smooth, controlled collagen creation, making it ideal for delicate areas.

The Science — How Definisse Works

Definisse uses microspheres of PDLLA, a dual-isomer of lactic acid polymer that stimulates collagen gently, evenly and reliably. PDLLA is considered gentler and smoother than some PLLA alternatives, making it ideal for midlife structural rejuvenation.

Mechanism

1The gel provides light immediate improvement
2PDLLA microspheres activate fibroblasts
3New collagen replaces the gel
4Tissue becomes firmer, thicker and smoother

Clinical Benefits

Increases Collagen Type I and Type III
Long-term structural regeneration over 18–30 months
Smooth, predictable collagen deposition
Excellent skin-firming effect
Particularly effective for women 40+ with hormonal thinning

What DEFINISSE® BIOSTIMULATOR Improvements

Face

Midface flattening
Early sagging
Jawline definition loss
Hollow cheeks
Lower face heaviness
Marionette folds
Nasolabial support
Menopause collagen decrease

Neck + Lower Face

Neck laxity
Fine crepiness
Under-chin skin thinning
Loss of elasticity

Skin Quality

Improved firmness
Better elasticity
Stronger structural foundation
Thicker, healthier dermal layers

Who Is Definisse For?

Want natural, regenerative improvementPrefer smooth, even collagen regenerationHave early-to-moderate facial ageingWant tissue firmness without added weightAre experiencing perimenopause or menopause skin declineWant long-lasting results without the “filler look”Would benefit from a combined approach with Definisse Threads

Particularly suitable for women 40–70+ depending on collagen status.

The Treatment Process

Consultation & Structural Assessment

Facial mapping of collagen-lost zones + ageing trajectory.

Treatment

Definisse is injected into deep support layers using your practitioner’s advanced regenerative protocols.

No Massage Required

Unlike PLLA-based biostimulators, PDLLA generally does not require at-home massage.

Gradual Collagen Build

Regeneration continues slowly and naturally over weeks and months.

Timeline of Results

Week 0–2

Soft hydration effect

Week 4–8

Early tissue firmness & support

Month 3–6

Visible lift + contour improvement

Month 6–30

Peak collagen remodelling & longevity

Safety

Definisse PDLLA biostimulator has an excellent safety profile when injected by trained professionals. Definisse is CE-approved and used internationally for collagen remodelling.

Mild swellingRednessTendernessBruising

Pricing Guidance

Pricing varies depending on treatment zones, number of vials, single session vs regenerative programme, and combined threads + PDLLA lift. Discussed at consultation to tailor an individualised plan.

Start Your Journey

Experience smooth, controlled collagen regeneration and long-lasting natural lift with one of the most advanced biostimulator systems available.

Book Your Definisse Biostimulator Consultation in Ware (SG12)