What Are Polynucleotides?
Polynucleotides (PDRN/PN/PNA) are DNA fragments derived from natural sources that repair the skin at a cellular level.
They activate fibroblasts, increase collagen, improve elasticity, restore hydration and reduce inflammation.
- Thickens & strengthens the skin
- Improves elasticity + firmness
- Hydrates from within
- Reduces inflammation + redness
- Excellent for tear troughs without filler
Best For
- ✔Menopause skin thinning
- ✔Fine lines
- ✔Under-eye crepiness
- ✔Acne scarring
- ✔Dull or fragile skin
- ✔Slow healing / inflammatory skin
Treats Conditions
This treatment is effective for the following conditions.
When Is This Appropriate?
Read the clinical context behind this treatment approach.
Menopause and Under-Eye Ageing: Why Creasing and Hollowness Accelerate
Discover why menopause accelerates under-eye creasing and hollowness. Nurse-led clinical insight from ULANDA in Ware, Hertfordshire.
Menopause and Collagen Loss: Why Structural Ageing Accelerates in Midlife
Understand why collagen loss accelerates during menopause and how structural ageing changes in midlife. Nurse-led clinical insight from ULANDA, Ware Hertfordshire.
Crepey Skin and Elasticity Loss: What It Means and How to Treat It Safely
Understand why crepey skin develops and how elasticity loss can be treated safely. Nurse-led clinical guidance from ULANDA in Ware, Hertfordshire.
Under-Eye Ageing in Menopause: Why Hollowness and Creasing Accelerate
Discover why under-eye hollowness and creasing accelerate during menopause. Nurse-led clinical insight from ULANDA in Ware, Hertfordshire.
Oestrogen, Collagen and Elasticity: Why Skin Changes Rapidly in Midlife
Learn how declining oestrogen affects collagen, elastin and skin elasticity in midlife. Nurse-led clinical insight from ULANDA in Ware, Hertfordshire.
Menopause and Skin Biology: How Hormonal Shifts Change Skin Behaviour
Discover how menopause affects collagen, elastin and barrier stability. Nurse-led clinical insight from ULANDA in Ware, Hertfordshire.
Repair at the Cellular Level
Book your Polynucleotides consultation at ULANDA.
The Ulanda Connection — How Polynucleotides Elevates Refresh, Renew & Restore
Protocol
AI skin analysis to identify thinning zones. Course of 2–4 sessions. Often combined with microneedling or PRP.
Results: 2–12 weeks, progressive. Downtime: Minimal.